Combination of aldose reductase inhibitors and selective...

Details Combination of aldose reductase inhibitors and selective... Combination of aldose reductase inhibitors and selective...

A - Human Necessities

61

K

A61K 31/502 (2006.01) A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 31/15 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/167 (2006.01) A61K 31/185 (2006.01) A61K 31/198 (2006.01) A61K 31/353 (2006.01) A61K 31/4184 (2006.01) A61K 31/4188 (2006.01) A61K 31/426 (2006.01) A61K 31/4406 (2006.01) A61K 31/451 (2006.01) A61K 31/4525 (2006.01) A61K 31/454 (2006.01) A61K 31/4747 (2006.01) A61K 31/517 (2006.01) A61K 31/5375 (2006.01) A61K 31/538 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01) A61P 9

Patent

CA 2327638

This invention is directed to methods, pharmaceutical compositions and kits comprising an aldose reductase inhibitor (ARI), a prodrug thereof or a pharmaceutically acceptable salt of said ARI or said prodrug and selective serotonin reuptake inhibitor (SSRI), a prodrug thereof or a pharmaceutically acceptable salt of said SSRI or said prodrug. This invention further relates to methods of using those pharmaceutical compositions for the treatment of diabetic complications such as diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, myocardial infarction, cataracts and diabetic cardiomyopathy.

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