Combination of alpha-2 receptor agonist (clonidin) and an...

A - Human Necessities – 61 – K

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A61K 31/415 (2006.01) A61K 31/216 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2642850

An alpha2 adrenoreceptor agonist eg. clonidine, brimonidine, monoxidine, lofexidine is useful for the treatment of siaiorrhoea, administered by the paraungual, sublingual or buccal route. The patient to be treated is also given an anti-muscarinic agent eg. oxybutynin, glycopyrrolate, ipratropium.

Un agoniste du récepteur adrénergique alpha 2 tel que la clonidine, la brimonidine, la monoxidine, la lofexidine est utile pour le traitement de la sialorrhée lorsqu'il est administré par voie paralinguale, sublinguale ou buccale. Le patient à traiter reçoit également un agent anti-muscarinique tel que l'oxybutynine, le glycopyrrolate, l'ipratropium.

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