Combination of an adenosine a2a receptor antagonist and an...

Details Combination of an adenosine a2a receptor antagonist and an... Combination of an adenosine a2a receptor antagonist and an...

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61K 31/53 (2006.01) A61K 45/06 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2459304

This invention relates to a method of treating depression and anxiety-related disorders comprising administering to a mammal in need of such treatment an effective amount of a combination of an adenosine A2A antagonist and an antidepressant or an anxiolytic; another aspect of the invention is a pharmaceutical composition comprising a therapeutically effective amount of a combination of an adenosine A2A antagonist and an antidepressant or anxiolytic in a pharmaceutically acceptable carrier.

La présente invention concerne une méthode de traitement de la dépression et des troubles liés à l'anxiété qui consiste à administrer à un mammifère nécessitant un tel traitement, une quantité efficace d'une combinaison d'un antagoniste d'adénosine A¿2A? et d'un antidépresseur ou d'un anxiolytique. Un autre aspect de cette invention se rapporte à une composition pharmaceutique comprenant une quantité thérapeutiquement efficace d'une combinaison d'un antagoniste d'adénosine A¿2A ?et d'un antidépresseur ou d'un anxiolytique incorporée dans un support pharmaceutiquement acceptable.

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