Combination of an ibat inhibitor and a metal salt for the...

Details Combination of an ibat inhibitor and a metal salt for the... Combination of an ibat inhibitor and a metal salt for the...

A - Human Necessities

61

K

A61K 33/42 (2006.01) A61K 31/00 (2006.01) A61K 31/554 (2006.01) A61K 33/06 (2006.01) A61K 33/14 (2006.01) A61P 1/12 (2006.01)

Patent

CA 2492374

A combination comprising an IBAT inhibitor, or a pharmaceutically acceptable salt, solvate of such a salt or a prodrug thereof, and a metal salt, wherein the metal salt is formulated to release in the terminal ileum, caecum and/or the colon, is described. Compositions containing this combination and uses of the combination are also described.

Cette invention a trait à une association médicamenteuse contenant un inhibiteur du transport d'acide biliaire iléal (IBAT) ou un sel de celui-ci, acceptable du point de vue pharmaceutique, d'un solvate de ce sel ou d'un promédicament, et d'un sel métallique. Ce sel métallique est conçu pour être libéré dans l'iléon terminal, le caecum et/ou le côlon. L'invention concerne également des compositions contenant cette association ainsi que les utilisations de cette association.

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