Combination of an indazolylaminopyrrolotriazine and taxane...

A - Human Necessities – 61 – K

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A61K 31/53 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2754909

Provided herein are methods of treating a proliferative disease in a subject, comprising administering to the subject a therapeutically effective amount of an indazolylaminopyrrolotriazine, e.g., a compound of Formula (I), and a taxane. Also provided herein are pharmaceutical compositions which comprise an indazolylaminopyrrolotriazine and taxane, in combination with one or more pharmaceutically acceptable excipients.

L'invention porte sur des procédés de traitement d'une maladie proliférative, chez un sujet, qui comprennent l'administration au sujet d'une quantité thérapeutiquement efficace d'une indazolylaminopyrrolotriazine, par exemple un composé de la formule (I), et d'un taxane. L'invention porte également sur des compositions pharmaceutiques qui comportent une indazolylaminopyrrolotriazine et un taxane, en combinaison avec un ou des excipients de qualité pharmaceutique.

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