Combination of antibodies and glucocorticoids for treating...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/30 (2006.01) A61K 31/573 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2606081

The invention relates to the use of glucocorticoids for producing medicaments for reducing or eliminating unwanted side effects caused by a non-specific cytokinin release during the treatment of diseases with immunostimulant antibodies. The invention also relates to a pharmaceutical composition containing at least one immunostimulant antibody and at least one glucocorticoid.

La présente invention concerne l'utilisation de glucocorticoïdes pour la fabrication de médicaments permettant de réduire ou éliminer les effets secondaires gênants apparaissant en raison d'une libération non spécifique de cytokine lors du traitement de maladies au moyen d'anticorps immunostimulants. L'invention concerne également une composition pharmaceutique contenant au moins un anticorps immunostimulant et au moins un glucocorticoïde.

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