A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/401 (2006.01) A61K 31/519 (2006.01) A61K 45/06 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2550848
The present invention relates to a combination of an inhaled / oral PDE 4 inhibitor in combination with inhaled anticholinergic bronchodilators (muscarinic receptor antagonists), preferentially Roflumilast or AWD-12-281 and R,R-glycopyrrolate, for symptomatic or prophylactic treatment of respiratory diseases, especially those accompanied by obstruction or inflammation such as chronic obstructive pulmonary disease (COPD) or asthma. It further comprises the presentation of this combination in a locally applied (inhaled) formulation and application in an inhalation device for instance in the Novolizer~.
L'invention concerne une combinaison d'un inhibiteur inhalé / oral PDE 4 combiné avec des bronchodilatateurs anticholinergiques inhalés (antagonistes du récepteur muscarinique), de préférence, Roflumilast ou AWD-12-281 et R,R-glycopyrrolate, pour le traitement symptomatique or prophylactique de maladies respiratoires, notamment celles accompagnées d'une obstruction ou d'une inflammation, telles que des maladies pulmonaires obstructives chroniques (COPD) ou l'asthme. L'invention concerne en outre la présentation de cette combinaison dans une formulation (inhalée) appliquée localement, ainsi que l'application dans un dispositif d'inhalation, par exemple, dans le Novolizer?.
Cnota Peter Juergen
Fyrnys Beatrix
Maus Joachim
Szelenyi Istvan
Marks & Clerk
Meda Pharma Gmbh & Co. Kg
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