Combination of dipeptidyl peptidase-iv inhibitor and a...

A - Human Necessities – 61 – K

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A61K 31/4985 (2006.01) A61K 31/44 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2606188

The present invention relates to pharmaceutical compositions comprising a combination of a particular dipeptidyl peptidase-IV (DPP-IV) inhibitor and a particular cannabinoid CB1#191 receptor antagonist/inverse agonist, kits containing such combinations and methods of using such compositions for the treatment of diabetes, diabetes associated with obesity, diabetes-related disorders, obesity, and obesity-related disorders.

L'invention concerne des compositions pharmaceutiques contenant une combinaison d'un inhibiteur particulier de la dipeptidyl peptidase-IV (DPP-IV) et d'un antagoniste/agoniste inverse particulier du récepteur CB1 cannabinoïde. L'invention concerne également des kits contenant ces combinaisons, ainsi que des méthodes d'utilisation de ces compositions dans le traitement du diabète, du diabète associé à l'obésité, des troubles liés au diabète, de l'obésité et des troubles liés à l'obésité.

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