A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/06 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2430298
This invention relates to pharmaceutical compositions comprising combinations of a GABA agonist, a prodrug thereof or a pharmaceutically acceptable salt of said GABA agonist or said prodrug and a SDI, a prodrug thereof or a pharmaceutically acceptable salt of said SDI or said prodrug, kits containing such combinations and methods of using such combinations to treat mammals, including humans, suffering from diabetic complications such as diabetic neuropathy, diabetic nephropathy, diabetic cardiomyopathy, diabetic retinopathy, diabetic microangiopathy, diabetic macroangiopathy, cataracts or foot ulcers.
La présente invention concerne des compositions pharmaceutiques comprenant des combinaisons d'un agoniste GABA, d'un promédicament associé ou d'un sel pharmaceutiquement acceptable de l'agoniste GABA ou du promédicament, et d'un inhibiteurs de la sorbitol-déshydrogénase (SDI), un promédicament de celui-ci ou un sel pharmaceutiquement acceptable de cet inhibiteur ou de ce promédicament. L'invention concerne également des trousses contenant de telles combinaisons et des méthodes d'utilisation de ces combinaisons pour traiter des mammifères, y compris les humains, souffrant de complications diabétiques telles que la neuropathie diabétique, la néphropathie diabétique, la cardiomyopathie diabétique, les cataractes ou les ulcères du pied.
Pfizer Products Inc.
Smart & Biggar
LandOfFree
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