Combination of iap inhibitors and flt3 inhibitors

Details Combination of iap inhibitors and flt3 inhibitors Combination of iap inhibitors and flt3 inhibitors

A - Human Necessities

61

K

A61K 31/427 (2006.01) A61K 31/437 (2006.01) A61K 31/553 (2006.01) A61K 31/704 (2006.01) A61K 31/7068 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2670498

The present invention relates to combinations of IAP inhibitors and FLT3 inhibitors, pharmacological compositions comprising said combination, methods of treating hematological malignancies, including acute myeloid leukemia (AML), comprising the combination of a compound that inhibits the binding of the second mitochondria-derived activator of caspase (Smac) protein to inhibitor of apoptosis (IAPs) (IAP inhibitor) and one or more pharmaceutically active agents and the use of these combinations for the treatment of acute myeloid leukemia; and a commercial package comprising said combination.

L'invention concerne des combinaisons d'inhibiteurs de IAP et d'inhibiteurs de FLT3, des compositions pharmacologiques comprenant une telle combinaison, des procédés de traitement de malignités hématologiques, notamment la leucémie aiguë myéloïde (LAM). Les compositions pharmacologiques de l'invention comprennent un composé inhibant la liaison de la protéine Smac (activateur de caspase dérivé de mitochondries dites secondaires) à l'inhibiteur d'apoptose (inhibiteur de IAP) combiné à au moins un principe pharmaceutiquement actif. L'invention concerne également l'utilisation de ces combinaisons pour traiter une leucémie aiguë myéloïde. L'invention concerne encore un conditionnement commercial contenant cette combinaison.

Affiliated with

Also associated with

Rating

Combination of iap inhibitors and flt3 inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Combination of iap inhibitors and flt3 inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combination of iap inhibitors and flt3 inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1939699