Combination of insulin with triazine derivatives and its use...

Details Combination of insulin with triazine derivatives and its use... Combination of insulin with triazine derivatives and its use...

A - Human Necessities

61

K

A61K 31/53 (2006.01) A61K 38/28 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2746479

The invention relates to a composition for use as a medicament comprising insulin in combination with at least one compound of formula (I), wherein the radicals R1 to R6 have the meaning according to claim 1, and/or physiologically acceptable salts thereof. Another object of the invention concerns a pharmaceutical composition comprising as active ingredients effective amounts of insulin and at least one compound of formula (I), together with pharmaceutically tolerable adjuvants, for the prophylactic or therapeutic treatment and/or monitoring of physiological and/or pathological conditions that are associated with insulin resistance. The invention also relates to a pharmaceutical package comprising insulin in a first dosage unit and at least one compound of formula (I) in a second dosage unit.

L'invention porte sur une composition pour utilisation en tant que médicament, comprenant de l'insuline en combinaison avec au moins un composé selon la formule (I), dans laquelle les radicaux R1 à R6 ont la signification selon la revendication 1, et/ou des sels physiologiquement acceptables de celui-ci. Un autre objectif de l'invention concerne une composition pharmaceutique comprenant en tant qu'ingrédients actifs des quantités efficaces d'insuline et au moins un composé selon la formule (I), conjointement avec des adjuvants pharmaceutiquement tolérables, pour le traitement prophylactique ou thérapeutique et/ou la surveillance d'états physiologiques et/ou pathologiques qui sont associés à une résistance à l'insuline. L'invention porte également sur un conditionnement pharmaceutique comprenant de l'insuline dans une première unité de dosage et au moins un composé de formule (I) dans une seconde unité de dosage.

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