Combination of pilocarpin and methimazol for treating...

A - Human Necessities – 61 – K

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Details

A61K 31/4178 (2006.01) A61K 31/197 (2006.01) A61K 31/4164 (2006.01) A61K 31/485 (2006.01) A61K 31/567 (2006.01) A61P 25/02 (2006.01)

Patent

CA 2727064

The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related peripheral neuropathies. More particularly, the invention relates to combined therapies for treating said disease by affecting simultaneously muscarinic receptor signalling and thyroid hormone pathway in a subject.

L'invention porte sur des compositions et des procédés destinés au traitement de la maladie de Charcot-Marie-Tooth et de neuropathies périphériques associées. En particulier, l'invention concerne des thérapies combinées qui permettent de traiter ladite maladie en agissant simultanément sur la signalisation du récepteur muscarinique et sur la voie de l'hormone thyroïde chez un sujet.

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