Combination of radio waves and pharmacologically active...

A - Human Necessities – 61 – N

Patent

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A61N 1/40 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2567477

The invention relates to a combination of radio waves and pharmacologically active substances selected from the group containing a) monoclonal antibodies and/or b) tyrosine-kinase inhibitors and/or c) angiogenesis inhibitors and/or d) farnesyl-transferase inhibitors and/or e) topoisomerase-I or topoisomerase- II inhibitors and/or f) cytokine and/or g) antisense oligonucleotides, optionally together with at least one chemotherapeutic agent. The invention also relates to the use of said combination for the prophylaxis and/or treatment of cancer, tumours and metastases.

L'invention concerne une combinaison d'ondes radio et de substances pharmaceutiquement actives sélectionnées dans le groupe comprenant a) des anticorps monoclonaux et/ou b) des inhibiteurs de tyrosine kinase et/ou c) des inhibiteurs d'angiogénèse et/ou d) des inhibiteurs de farnésyl transférase et/ou e) des inhibiteurs de topoisomérase-I ou -II et/ou f) de la cytokine et/ou g) des oligonucléotides antisens, cette combinaison pouvant éventuellement comporter un ou plusieurs produits de chimiothérapie. La présente invention porte également sur l'utilisation de cette combinaison pour le traitement prophylactique et/ou thérapeutique du cancer, de tumeurs et de métastases.

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