Combination of reboxetine and a cyclooxygenase-2 inhibitor

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/5375 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2510584

A method of treating, preventing, or inhibiting a CNS disorder and/or pain and inflammation, or an inflammation-associated disorder in a subject in need of such treatment, prevention, or inhibition provides for treating the subject with reboxetine and a cyclooxygenase-2 selective inhibitor or prodrug thereof, wherein the amount of reboxetine and the amount of a cyclooxygenase-2 selective inhibitor or prodrug thereof together constitute a CNS disorder and/or pain and inflammation or inflammation-associated disorder suppressing treatment, prevention, or inhibition effective amount of the composition. Compositions and pharmaceutical compositions that contain reboxetine and a cyclooxygenase-2 selective inhibitor are also disclosed.

L'invention porte sur une méthode de traitement, prévention ou inhibition d'un trouble du SNC et/ou de la douleur et des inflammations ou de troubles associés à l'inflammation chez un patient le nécessitant consistant à traiter le patient avec de la réboxétine et un inhibiteur sélectif de la cyclooxygénase-2 ou son promédicament, en quantités efficace pour assurer le traitement, la prévention ou l'inhibition. L'invention porte également sur des compositions et préparations pharmaceutiques contenant de la réboxétine et un inhibiteur sélectif de la cyclooxygénase-2.

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