Combination of rosiglitazone and donepezil for improvement...

Details Combination of rosiglitazone and donepezil for improvement... Combination of rosiglitazone and donepezil for improvement...

A - Human Necessities

61

K

A61K 31/4439 (2006.01) A61K 31/445 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2623204

The invention relates inter alia to a pharmaceutical composition comprising both rosiglitazone or a pharmaceutically acceptable salt thereof and donepezil or a pharmaceutically acceptable salt thereof which is of use in the treatment or prophylaxis of Alzheimer's disease or other dementias and mild cognitive impairment. The invention also relates to oral dosage forms comprising rosiglitazone or a pharmaceutically acceptable salt thereof and donepezil or a pharmaceutically acceptable salt thereof.

L'invention concerne notamment une composition pharmaceutique comprenant à la fois la rosiglitazone ou un sel de celle-ci pharmaceutiquement acceptable et le donépézil ou un sel de celui-ci pharmaceutiquement acceptable, que l'on utilise dans le traitement ou la prophylaxie de la maladie d'Alzheimer ou d'autres démences et déficiences cognitives légères. L'invention concerne également des formes posologiques orales comprenant la rosiglitazone ou un sel de celle-ci pharmaceutiquement acceptable et le donépézil ou un sel de celui-ci pharmaceutiquement acceptable.

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