Combination of sodium channel blockers and their derivatives...

Details Combination of sodium channel blockers and their derivatives... Combination of sodium channel blockers and their derivatives...

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61K 35/60 (2006.01) A61P 25/04 (2006.01) A61P 25/18 (2006.01) A61P 25/36 (2006.01) A61K 31/7048 (2006.01)

Patent

CA 2601831

The present invention refers to a new combination of sodium channel blockers, especially Tetrodotoxin, and their derivatives with opioid antagonists, especially naloxone, according medicinal products for human and/or animal therapeutics and their use for the treatment of a variety of diseases, especially pain, preferably neuropathic pain.

La présente invention concerne une nouvelle combinaison de bloqueurs des canaux sodiques, en particulier la tétrodotoxine, et de dérivés de ceux-ci avec des antagonistes opioïdes, en particulier la naloxone, à usage médical et/ou vétérinaire, ainsi que l'utilisation de cette combinaison pour le traitement de diverses maladies, en particulier la douleur et, de préférence, la douleur névropathique.

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