G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/573 (2006.01) G01N 33/68 (2006.01) G01N 33/92 (2006.01)
Patent
CA 2757221
The present invention related to a method of identifying a subject having or at risk of having or developing a cardiovascular disease and/or a cardiovascular event, comprising: - measuring, in a sample obtained from said subject, at least two cardiovascular risk factors: a) sPLA2 activity and b) oxidized phospholipids on apolipoprotein B-100 particles (Ox PL/apo B), - combining said measurements, the combined value of s PLA2 activity and Ox PL/apo B being indicative of having or a risk of having or developing a cardiovascular disease and/or cardiovascular event.
La présente invention concerne un procédé didentification dun sujet ayant ou présentant un risque davoir ou de développer une maladie cardiovasculaire et/ou un événement cardiovasculaire, comprenant : - la mesure, dans un échantillon obtenu du sujet, dau moins deux facteurs de risque cardiovasculaire : a) lactivité sPLA2 et b) des phospholipides oxydés sur des particules dapolipoprotéine B-100 (Ox PL/apo B), - la combinaison desdites mesures, la valeur combinée de lactivité sPLA2 et de Ox PL/apo B indiquant la présence ou un risque davoir ou de développer une maladie cardiovasculaire et/ou un événement cardiovasculaire.
Mallat Ziad
Tedgui Alain
Tsimikas Sotirios
Witztum Joseph
Goudreau Gage Dubuc
Inserm (institut National de La Sante Et de La Recherche Medical
The Regents Of The University Of California
Universite Paris Diderot ( Paris 7)
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