Combination pediatric vaccine with enhanced immunogenicity...

A - Human Necessities – 61 – K

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A61K 39/102 (2006.01) A61K 39/385 (2006.01)

Patent

CA 2109159

COMBINATION PEDIATRIC VACCINE WITH ENHANCED IMMUNOGENICITY OF EACH VACCINE COMPONENT ABSTRACT OF THE INVENTION A combined pediatric vaccine composition featuring, in a single immunizing dose, a mixture of diphtheria, tetanus and pertussis antigens and a conjugate of fragments of the capsular polysaccharide antigen of Haemophilus influenzae type b and CRM197 protein in a pharmaceutically acceptable aqueous vehicle is provided. The combined vaccine composition exhibits an enhanced antibody response by infants to each of the four vaccine components.

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