A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/219
A61K 31/60 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 487/04 (2006.01) C07C 69/14 (2006.01)
Patent
CA 1247529
Abstract of the disclosure: Combination product containing A) on the one hand a pyrimido-pyrimidine of the formula I Image I in which at least one of the radicals R1 and R3 represents the radical -N(CH2-CHR5-OH)2 where R5 = hydrogen or methyl, and at least one of the radicals R2 and R4 repre- sents the radical Image which can also be interrupted by oxygen in the p-position relative to the nitrogen atom, or active metabolites and/or salts thereof, and B) on the other hand O-acetylsalicylic acid or pharmaceutically tole- rated salts thereof, the weight ratio of component A) to component B) being greater than 0.5, with or without C) a pharmaceutical vehicle, for sequential administration in the therapy of diseases caused or characterized by impaired blood functions or constituents of blood, in particular platelets or erythrocytes, in a manner such that component A) is released first, its use in human and veterinary medicine, and a process for the preparation of pharmaceu- tical formulations.
487159
Seiffge Dirk
Weithmann Klaus U.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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