A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/220
A61K 31/52 (2006.01)
Patent
CA 1247530
-1- Abstract of the Disclosure: A combination product containing A) on the one hand a xanthine derivative of the formula Image (I) in which one of the radicals R1 and R3 represents a straight-chain alkyl, (.omega.-1)-oxoalkyl or (.omega.-1)-hydroxy- alkyl group having 3 to 8 carbon atoms, and the two other radicals R2 and R3, or R1 and R2 represent straight- chain or branched alkyl groups having 1 to 8 carbon atoms in the position of R1 and R3 and 1 to 4 carbon atoms in the position of R2, the maximum total of carbon atoms in these two alkyl substituents being 10, or of the formula Image (II) in which R represents an alkyl radical having 1 to 4 carbon atoms, or prodrug forms of the oxoalkylxanthines of the formula I and II or of the hydroxylalkylxanthine of the formula I, or its metabolites, and B) on the other hand O-acetylsalicylic acid or its phar- macologically tolerated salts, C) with or without a pharmaceutical vehicle, for sequential administration in the treatment of disea- ses caused or characterized by impaired constituents of blood, in particular platelets or erythrocytes, but also - 2 - leukocytes, in such a manner that component A) is released first, and its use in human and veterinary medicine.
485956
Seiffge Dirk
Weithmann Klaus U.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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