Combination therapies for cancer and proliferative angiopathies

Details Combination therapies for cancer and proliferative angiopathies Combination therapies for cancer and proliferative angiopathies

A - Human Necessities

61

K

A61K 31/282 (2006.01) A61K 31/7064 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2563305

Compositions and methods for treating cancer and proliferative angiopathies are provided. A composition can include an inhibitor of the Jak2/Stat3 signaling pathway and an inhibitor of the PI3k/Akt signaling pathway. In certain cases, the two inhibitors are capable of acting synergistically as compared to either inhibitor alone.

L'invention concerne des compositions et des procédés permettant de traiter le cancer et des angiopathies proliférantes. Une composition de cette invention peut comprendre un inhibiteur du trajet de signalisation Jak2/Stat3 et un inhibiteur du trajet de signalisation PI3k/Akt. Dans certains cas, les deux inhibiteurs sont capables d'agir en synergie, par opposition à chaque inhibiteur seul.

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