Combination therapy

Details Combination therapy Combination therapy

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/395 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2659463

Methods to mobilize progenitor and/or stem cells from the bone marrow to the bloodstream by administering a combination of at least one CXCR4 inhibitor and at least one VLA-4 inhibitor are described. The combinations may also be used to treat multiple myeloma.

Les procédés décrits permettent de mobiliser des précurseurs et/ou cellules souches de la moelle osseuse dans la circulation sanguine, par administration d'une combinaison d'au moins un inhibiteur de CXCR4 et d'au moins un inhibiteur de VLA-4. Les combinaisons peuvent également être utilisées pour traiter le myélome multiple.

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