Combination therapy comprising the use of et-743 and...

Details Combination therapy comprising the use of et-743 and... Combination therapy comprising the use of et-743 and...

A - Human Necessities

61

K

A61K 31/495 (2006.01) A61K 31/337 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2545054

Methods of treating a human body for cancer are provided. In one aspect, an effective therapeutic amount of paclitaxel is administered in combination with ET-743 in a dose range between 0.5 and 1 mg/m2. In a related aspect, an effective therapeutic amount of ET-743 is administered in combination with paclitaxel in a dose range between 80 and 140 mg/m2.

L'invention porte sur des méthodes de traitement du cancer humain. Selon l'un de ses aspects, on administre une dose à effet thérapeutique de paclitaxel combinée à de l'ET-743 à raison de 0,5 à 1 mg/m?2¿. Selon un autre de ses aspects, on administre une dose à effet thérapeutique de ET-743 combinée à du paclitaxel à raison de 80 à 140 mg/m?2¿.

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