Combination therapy for hiv infection using the hiv protease...

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) A61K 31/18 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/505 (2006.01) A61K 31/513 (2006.01) A61K 31/7068 (2006.01) A61K 31/7072 (2006.01) A61P 31/18 (2006.01) C07H 19/00 (2006.01)

Patent

CA 2211973

The combination of the HIV protease inhibitor Compound J, 3TC, and, optionally AZT, ddI, or ddC, is useful in the inhibition of HIV protease, the inhibition of HIV reverse transcriptase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

L'association du composé J, un inhibiteur de la protéase de VIH, de 3TC et, éventuellement, d'AZT, ddI ou ddC, convient à l'inhibition de la protéase de VIH, à l'inhibition de la transcriptase inverse de VIH, à la prévention ou au traitement d'une infection à VIH et au traitement du SIDA, sous forme de composés, de sels pharmaceutiquement acceptables ou de principes actifs de compositions pharmaceutiques, éventuellement en association avec d'autres antiviraux, immunomodulateurs, antibiotiques ou vaccins. Des procédés de traitement du SIDA et de prévention ou de traitement d'une infection à VIH sont également décrits.

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