Combination therapy for the treatment of immunoinflammatory...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61K 31/00 (2006.01) A61K 38/13 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2514061

The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non- steroidal immunophilin-dependent immunosuppressant (NsIDI) and an NsIDI enhancer (NsIDIE) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and NsIDIE or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.

Selon cette invention, une méthode de traitement d'un patient chez qui on a diagnostiqué, ou qui risque de développer, un trouble immuno-inflammatoire consiste à administrer au patient un immunosuppresseur dépendant de l'immunophilline non stéroïdien (NsIDI) ainsi qu'un activateur de NsIDI (NsIDIE) ou un analogue ou un métabolite de celui-ci. Cette invention concerne également une composition pharmaceutique contenant un NsIDI et un NsIDIE ou un analogue ou un métabolite de celui-ci servant au traitement ou à la prévention d'un trouble immuno-inflammatoire.

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