Combination therapy for the treatment of obesity

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/506 (2006.01) A61K 31/4155 (2006.01) A61K 31/4192 (2006.01) A61K 31/438 (2006.01) A61K 31/4747 (2006.01) A61K 31/497 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2492225

The present invention relates to compositions comprising a NPY5 antagonist of formula I or II and an anti-obesity agent, useful for the treatment and prevention of diabetes, obesity and obesity-related disorders. The present invention further relates to methods of treating or preventing obesity and obesity-related disorder in a subject in need thereof by administering a composition of the present invention. The present invention further provides for pharmaceutical compositions, medicaments, and kits useful in carrying out these methods.

L'invention concerne des compositions renfermant un antagoniste NPY5 de formule I ou II et un agent anti-obésité, qui sont utiles pour le traitement et la prévention du diabète, de l'obésité et des troubles liés à l'obésité. L'invention concerne également des procédés de traitement ou de prévention de l'obésité et des troubles liés à l'obésité chez un sujet, par l'administration d'une composition du type considéré. L'invention concerne par ailleurs des compositions pharmaceutiques, des médicaments et des kits utiles pour la mise en oeuvre des procédés susmentionnés.

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