A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4439 (2006.01) A61K 31/4015 (2006.01) A61K 31/4035 (2006.01) A61K 31/454 (2006.01)
Patent
CA 2624440
This invention concerns compositions for the treatment of urinary frequency, urinary urgency and urinary incontinence comprising (R)-N-[4-[2-[[2-hydroxy-2- (pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4-[4-(4-trifluoromethylphenyl)thiazol- 2-yl]benzenesulfonamide and pharmaceutically acceptable salts thereof. In another aspect, this invention concerns combination therapy for urinary frequency, urinary urgency and urinary incontinence wherein one of the active agents is (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4- [4-(4-trifluoromethylphenyl)thiazol-2-yl]benzenesulfonamide and pharmaceutically acceptable salts thereof.
L'invention concerne des compositions destinées au traitement de la pollakiurie, de la miction impérieuse et de l'incontinence urinaire et comprenant : (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3-yl)éthyl]amino]éthyl]phényl]-4-[4-(4-trifluorométhylphényl)thiazol-2-yl]benzènesulfonamide et des sels acceptables sur le plan pharmaceutique de celui-ci. Dans un autre mode de réalisation, l'invention concerne une polythérapie destinée à la pollakiurie, la miction impérieuse et l'incontinence urinaire, un des principes actifs étant (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3-yl)éthyl]amino]éthyl]phényl]-4-[4-(4-trifluorométhylphényl)thiazol-2-yl]benzènesulfonamide et des sels acceptables sur le plan pharmaceutique de celui-ci.
Gottesdiener Keith M.
Green Stuart A.
Macintyre Euan
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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