Combination therapy for treating protein deficiencies

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 31/445 (2006.01) A61K 31/70 (2006.01) A61K 38/43 (2006.01) A61K 38/47 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2516304

This application provides methods of improving gene therapy by combining gene therapy with active site-specific chaperones (ASSCs). The ASSC increases the stability and efficiency of the protein encoded by the recombinant gene that is administered.

Cette invention se rapporte à des procédés servant à améliorer une thérapie génique en combinant la thérapie génique avec des molécules chaperonnes spécifiques des sites actifs (ASSC). La molécule chaperonne ASSC accroît la stabilité et l'efficacité de la protéine codée par le gène recombiné qui est administré.

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