A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/47 (2006.01) C12N 9/40 (2006.01)
Patent
CA 2514642
This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of the protein being administered. The application further provides compositions comprising the purified protein and an ASSC, and methods of treatment by administering the compositions.
L'invention concerne des méthodes permettant d'améliorer une thérapie par remplacement de protéines par combinaison d'une thérapie par remplacement de protéines à des chaperons spécifiques de site actif (ASSC) afin d'améliorer la stabilité et l'efficacité de la protéine administrée. L'invention concerne en outre des compositions comprenant la protéine purifiée et un ASSC, et des méthodes de traitement consistant à administrer ces compositions.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Mount Sinai School Of Medicine Of New York University
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