Combination therapy for treatment of autoimmune diseases...

A - Human Necessities – 61 – K

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Details

A61K 39/395 (2006.01) A61K 31/445 (2006.01) A61K 38/13 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) A61P 37/00 (2006.01) A61P 37/06 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2422076

The present invention concerns treatment of autoimmune diseases with the combination of an immunoregulatory antibody, e.g. and anti-B7.1 or anti-B7.2 or anti-CD40L antibody and at least one B cell antibody, such as CD19, CD20, CD22, CD23, or CD37, wherein such antibodies may be administered separately, or in combination, and in either, over prolonged periods of time.

La présente invention concerne le traitement de maladies auto-immunes à l'aide de la combinaison d'un anticorps immunorégulateur, p. ex. un anticorps anti-B7.1 ou anti-B7.2 ou anti-CD40L, et d'au moins un anticorps des cellules B, tels que CD19, CD20, CD22, CD23, or CD37. Selon ladite invention, ces anticorps peuvent être administrés séparément ou en combinaison, et des deux façons, sur des périodes de temps prolongées.

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