Combination therapy for treatment of refractory depression

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/551 (2006.01) A61K 31/135 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2332814

The invention provides methods and ocmpositions for the treatment of depressive states refractory to treatment with traditional anti-depressive therapies alone. These methods and compositions employ a compound having activity as an atypical antipsychotic and a serotonin reuptake inhibitor. This invention also provides methods of providing rapid onset treatments of major depression which employing a compound having activity as an atypical antipsychotic and a serotonin reuptake inhibitor.

L'invention concerne des méthodes et des compositions de traitement d'états dépressifs résistants au traitement par des thérapies anti-dépressives classiques seules. Ces méthodes et compositions utilisent un composé ayant une activité de neuroleptique atypique et un inhibiteur du recaptage de la sérotonine. Cette invention a également trait à des méthodes fournissant des traitements à effet rapide de la dépression majeure, lesquels utilisent un composé ayant une activité de neuroleptique atypique et un inhibiteur du recaptage de la sérotonine.

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