A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/505 (2006.01) A61K 31/335 (2006.01)
Patent
CA 2246419
This invention provides combination therapy methods, pharmaceutical combinations and compositions for inducing tumor cell regression in cancer patients, particularly metastatic breast cancer patients. The combination methods, combinations and compositions employ both edatrexate and a taxane (e.g. Paclitaxel) which are administered simultaneously or sequentially. The combination therapy described here permits the administration of unusually high doses of edatrexate.
L'invention concerne un traitement associé, des combinaisons et des compositions pharmaceutiques pour induire une régression des cellules tumorales chez des patients atteints d'un cancer, en particulier les patientes atteintes de cancer du sein, avec des métastases. Le traitement associé, les combinaisons et les compositions font appel simultanément à l'édatrexate et à un taxane (par exemple, le Paclitaxel) et ces médicaments sont administrés simultanément ou successivement. Le traitement associé décrit permet l'administration de doses particulièrement élevées d'édatrexate.
Fennelly David W.
Sirotnak Francis M.
Ade & Company
Sloan-Kettering Institute For Cancer Research
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