Combination therapy of...

Details Combination therapy of... Combination therapy of...

A - Human Necessities

61

K

A61K 31/551 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2648371

The present invention relates to novel combination therapies of (2R,Z)-2-amino-2- cyclohexyl-N-(5-(1-methyl-1 H-pyrazol-4-yl)-1-oxo-2,6-dihydro-1 H-[1,2]diazepino[4,5,6-cd]indol-8- yl)acetamide (compound 1 ), a pharmaceutically acceptable salt or solvates thereof, or a mixture thereof, in combination with an anti-cancer agent or radiation therapy.

La présente invention concerne de nouvelles polythérapies à base de (2R,Z)-2-amino-2-cyclohexyl-N-(5-(1-méthyl-1H-pyrazol-4-yl)-1-oxo-2,6-dihydro-1 H-[1,2]diazépino[4,5,6-cd]indol-8-yl)acétamide (composé 1), d'un sel pharmaceutiquement acceptable ou de solvates de ceux-ci, ou d'un mélange de ceux-ci, en association avec un agent anticancéreux ou une radiothérapie.

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