Combination therapy of hiv fusion/entry inhibitors targeting...

Details Combination therapy of hiv fusion/entry inhibitors targeting... Combination therapy of hiv fusion/entry inhibitors targeting...

C - Chemistry, Metallurgy

07

K

C07K 14/16 (2006.01) A61K 38/16 (2006.01) A61K 39/21 (2006.01)

Patent

CA 2734081

Provided herein are pharmaceutical compositions for the prophylactic and therapeutic treatment of HIV comprising combinations of HIV fusion/entry inhibitors with different target sites in HIV gp41 or different mechanisms of action. Also disclosed are methods of treating HIV infection by administering such compositions.

La présente invention porte sur des compositions pharmaceutiques destinées au traitement prophylactique et thérapeutique du VIH, comprenant des combinaisons d'inhibiteurs de fusion/entrée du VIH avec différents sites cibles dans gp41 du VIH ou différents mécanismes d'action. L'invention porte également sur des procédés de traitement d'une infection par le VIH par l'administration de telles compositions.

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