A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/42 (2006.01) A61K 31/57 (2006.01) A61K 31/58 (2006.01) A61P 31/14 (2006.01) C07K 16/10 (2006.01)
Patent
CA 2407292
Therapeutically effective anti-viral compositions, useful especially against respiratory diseases caused or mediated by respiratory syncytial virus (RSV) are disclosed, wherein said compositions comprise at least one anti-RSV antibody, including high affinity antibodies, and an additional anti- inflammatory agent, especially corticosteroids, as well as anti-inflammatory antibodies, especially anti-interleukin-6. Also disclosed are methods of using such compositions to treat and/or prevent respiratory diseases. Such compositions may optionally contain other non-antibody anti-viral agents.
L'invention concerne des compositions anti-virales efficaces au plan thérapeutique, utiles notamment contre les maladies respiratoires induites ou médiées par le virus respiratoire syncytial (RS). Lesdites composition comprennent au moins un anticorps anti-virus RS, dont des anticorps d'affinité élevée, et un agent anti-inflammatoire supplémentaire, notamment des corticostéroïdes, ainsi que des anticorps anti-inflammatoires, notamment des anti-interleukine-6. L'invention porte également sur des procédés d'utilisation desdites compositions pour le traitement et/ou la prévention de maladies respiratoires. Lesdites compositions peuvent éventuellement contenir d'autres agents anti-viraux non-anticorpaux.
Johnson Leslie S.
Prince Gregory
Medimmune Inc.
Smart & Biggar
Virion Systems Inc.
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