A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/42 (2006.01) A61K 31/70 (2006.01) A61P 31/14 (2006.01) C07K 16/10 (2006.01) C07K 16/24 (2006.01)
Patent
CA 2409689
Therapeutically effective anti-microbial compositions, useful especially against respiratory diseases caused or mediated by viruses, bacteria, and other respiratory parasites are disclosed, wherein said compositions comprise at least one neutralizing antibody, including high affinity antibodies, and an additional anti-infectious agent, such as an antiviral agent, for example, ribavirin, amantadine, rimantadine, or a neuraminidase-inhibitor or anti- bacterial agents, including other antibodies. Also disclosed are methods of using such compositions to treat and/or prevent respiratory and related diseases.
L'invention concerne des compositions antimicrobiennes thérapeutiquement efficaces, particulièrement utiles contre des maladies respiratoires causées ou induites par des virus, des bactéries et d'autres parasites respiratoires. Ces compositions renferment au moins un anticorps neutralisant, y comprise des anticorps d'affinité élevée, et un agent anti-infectieux additionnel, tel qu'un agent antiviral, par exemple ribavirine, amantadine, rimantadine ou un inhibiteur de la neuraminidase, ou des agents antibactériens, y compris d'autres anticorps. L'invention concerne également des procédés d'utilisation de telles compositions pour traiter et/ou prévenir des maladies respiratoires et apparentées.
Medimmune Inc.
Smart & Biggar
LandOfFree
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