C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A01N 43/04 (2006.01) A61K 38/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2624796
Provided herein is a method for reducing the amount of steroid required for the prevention, amelioration and/or treatment of pulmonary inflammation and/or airway hyperresponsiveness, comprisi administration of the steroid and an oligonucleotide targeted to IL-4R alpha. Also described is a method for the prevention, amelioration and/or treatment of pulmonary inflammation and/or airway hyperresponsiveness comprising administration of a corticosteroid and an oligonucleotide targeted to EL 4R alpha. Further provided are compositions comprising a corticosteroid and an EL-4R alpha targeted antisense oligonucleotide.
L'invention concerne un procédé servant à réduire la quantité de stéroïde requise pour la prévention, l'amélioration et/ou le traitement d'une inflammation pulmonaire et/ou d'une hyperréactivité bronchique, comprenant l'administration du stéroïde et d'un oligonucléotide ciblant le récepteur IL-4R alpha. L'invention concerne également un procédé pour la prévention, l'amélioration et/ou le traitement d'une inflammation pulmonaire et/ou d'une hyperréactivité bronchique comprenant l'administration d'un corticostéroïde et d'un oligonucléotide ciblant le récepteur IL-4R alpha. L'invention concerne en outre des compositions comprenant un corticostéroïde et un oligonucléotide antisens ciblant le récepteur IL-4R alpha.
Gregory Susan
Karras James G.
Isis Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
Combination therapy using budesonide and antisense... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Combination therapy using budesonide and antisense..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combination therapy using budesonide and antisense... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1778424