Combination therapy using immunotoxins with interleukin-2

Details Combination therapy using immunotoxins with interleukin-2 Combination therapy using immunotoxins with interleukin-2

C - Chemistry, Metallurgy

07

K

167/129

C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1285875

ABSTRACT OF THE DISCLOSURE Anti-tumor activity in humans can be augmented by administering to the mammalian host a pharmacologically effective amount of mammalian IL-2 and at least one monoclonal antibody that binds selectively to human tumor cells and/or at least one immunotoxin that binds selectively to human tumor cells. The IL-2 and immunotoxin and/or monoclonal antibody are preferably administered separately to the host. The composition is useful for prophylactic or therapeutic treatment of such cancers as ovarian and breast cancer.

542935

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