Combination therapy using nucleic acids and conventional drugs

Details Combination therapy using nucleic acids and conventional drugs Combination therapy using nucleic acids and conventional drugs

C - Chemistry, Metallurgy

12

N

C12N 15/87 (2006.01) A61K 41/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2325561

The present invention relates to methods for increasing the efficiency of transformation of cycling cells, the methods comprising synchronizing cells at a first stage of the cell cycle, and transforming the cells at a second stage of the cell cycle within about one cell cycle of the first stage with a genetically engineered nucleic acid that encodes a desired gene product. The invention further relates to cancer therapy and, in particular, to methods of efficiently transforming cancer cells with nucleic acids that encode gene products that inhibit the growth of cancer cells.

La présente invention concerne des méthodes permettant d'améliorer l'efficacité de la transformation de cellules à cycle. Ces méthodes consistent à synchroniser des cellules dans un premier stade du cycle cellulaire, puis à transformer ces cellules, dans un second stade du cycle cellulaire en l'espace d'environ un cycle cellulaire du premier stade, avec un acide nucléique obtenu par génie génétique codant un produit génique voulu. L'invention concerne également une thérapie anticancéreuse et, en particulier, des méthodes permettant de transformer efficacement des cellules cancéreuses avec des acides nucléiques codant des produits géniques inhibant la croissance de cellules cancéreuses.

Affiliated with

Also associated with

Rating

Combination therapy using nucleic acids and conventional drugs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Combination therapy using nucleic acids and conventional drugs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combination therapy using nucleic acids and conventional drugs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2022529