Combination therapy using transferrin fusion proteins...

A - Human Necessities – 61 – K

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A61K 51/06 (2006.01) A61K 51/08 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2575756

The present invention provides combination therapy comprising transferrin fusion protein and DPP-IV inhibitors and/or neutral endopeptidase (NEP) inhibitors. The transferrin fusion protein comprises therapeutic polypeptides or peptides useful in the treatment of diseases such as diabetes.

Cette invention a pour objet une polythérapie basée sur l~utilisation d~une protéine hybride de la transferrine et des inhibiteurs DPP-IV et/ou des inhibiteurs de l~endopeptidase neutre (NEP). La protéine hybride de la transferrine contient des polypeptides thérapeutiques ou des peptides utiles pour traiter certaines maladies dont le diabète.

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