Combination therapy with sglt-2 inhibitors and their...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/7004 (2006.01) A61K 31/155 (2006.01) A61K 31/445 (2006.01) A61K 31/64 (2006.01) A61K 31/7048 (2006.01) A61K 31/706 (2006.01) A61P 3/00 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2669043

The present invention is directed to a pharmaceutical composition comprised of one or more SGLT-2 inhibitor compound(s) in combination with one or more therapeutic agents which is suitable for the treatment of metabolic disorders including type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance, hyperglycemia, postprandial hyperglycemia, overweight, obesity, including class I obesity, class II obesity, class III obesity, visceral obesity and abdominal obesity, and metabolic syndrome.

L'invention concerne une composition pharmaceutique comprenant un ou plusieurs composés inhibiteurs de SGLT-2 combinés avec un ou plusieurs agents thérapeutiques. Cette composition pharmaceutique est appropriée dans le traitement des troubles métaboliques comprenant le diabète insulinodépendant, le diabète non insulinodépendant, une altération de la tolérance au glucose, l'hyperglycémie, l'hyperglycémie postprandiale, le surpoids, l'obésité, y compris l'obésité de classe I, l'obésité de classe II, l'obésité de classe III, l'obésité viscérale et l'obésité abdominale, et le syndrome métabolique.

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