A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/737 (2006.01) A61K 31/727 (2006.01) A61K 31/728 (2006.01)
Patent
CA 2606880
The present invention is directed to a method of treating patients suffering from nephropathy of diabetic origin by administration of sulodexide in combination with a blood pressure reducing agent, such as an inhibitor of an angiotensin converting enzyme (ACE inhibitor) and/or with an angiotensin II receptor blocker (ARB). The effectiveness of sulodexide with an ACE inhibitor or an ARB has been shown by the significant decrease of the albuminuria in microalbuminuric diabetic patients.
La présente invention concerne un procédé de traitement de patients souffrant de néphropathie d~origine diabétique en administrant du sulodexide en combinaison avec un agent de réduction de la pression sanguine, tel qu~un inhibiteur d~une enzyme convertissant l~angiotensine (inhibiteur ACE) et/ou avec un bloqueur (ARB) de récepteur de l~angiotensine II. L~efficacité du sulodexide avec un inhibiteur ACE ou un ARB a été montrée au moyen de la diminution significative de l~albuminurie chez les patients diabétiques microalbuminuriques.
Keryx Biopharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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