Combination therapy with triterpenoid compounds and...

A - Human Necessities – 61 – K

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Details

A61K 31/704 (2006.01) A61K 31/69 (2006.01) A61K 38/02 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61K 36/48 (2006.01)

Patent

CA 2595749

The present invention provides therapeutic compositions comprising a natural triterpenoid and a proteasome inhibitor. These compositions will be particularly useful in the treatment of malignancies and inflammation. The present invention also provides methods of treating a subject having a malignancy or an inflammatory disorder comprising administering to the subject a natural triterpenoid and a proteasome inhibitor.

La présente invention concerne des compositions thérapeutiques comprenant un triterpénoïde naturel et un inhibiteur de protéasome. Ses compositions conviendront particulièrement pour le traitement de tumeurs malignes et d'inflammation. Cette invention concerne aussi des techniques de traitement d'un sujet atteint d'une tumeur mènent ou d'un trouble inflammatoire qui consistent à administrer à ce sujet un triterpenoïde naturel et un inhibiteur de protéasome.

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