Combination treatment for depression and anxiety

Details Combination treatment for depression and anxiety Combination treatment for depression and anxiety

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/438 (2006.01) A61K 31/439 (2006.01) A61K 31/451 (2006.01) A61K 31/453 (2006.01) A61K 31/454 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/538 (2006.01) A61K 38/17 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2324813

The present invention relates to a method of treating depression or anxiety in a mammal, including a human, by administering to the mammal a CNS-penetrant NK-1 receptor antagonist e.g., a substance P receptor antagonist) in combination with an antidepressant or an anxiolytic agent. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier, a CNS-penetrant NK-1 receptor antagonist and an anxiolytic agent or antidepressant.

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