Combination treatment for depression and anxiety

Details Combination treatment for depression and anxiety Combination treatment for depression and anxiety

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 31/46 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/5375 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01) A61P 25/06 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2357901

The present invention relates to a method of treating depression or anxiety in a mammal, including a human, by administering to the mammal a CNS-penetrant NK-1 receptor antagonist (e.g., a substance P receptor antagonist) in combination with an NK- 3 antagonist agent. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier, a CNS-penetrant NK-1 receptor antagonist and an NK-3 antagonist.

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