Combination treatment with t-pa variant and low molecular...

Details Combination treatment with t-pa variant and low molecular... Combination treatment with t-pa variant and low molecular...

A - Human Necessities

61

K

A61K 38/57 (2006.01) A61K 38/49 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2372708

[0103] The invention concerns an improved therapeutic regimen for the treatment of thrombolytic disorders, such as acute myocardial infarction (AMI). In particular, the present invention concerns the treatment of thrombolytic disorders, e.g. AMI, with a combination of a tissue plasminogen activator (t-PA) variant having improved fibrin specificity and extended plasma half-life when compared with wild-type human t-PA and a low molecular weight heparin.

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