A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) C07K 16/40 (2006.01) C12N 9/64 (2006.01)
Patent
CA 2741492
Provided are methods and compositions for using protease binding proteins in combination with other therapeutic agents to treat inflammatory disorders such as rheumatoid arthritis, psoriasis, multiple sclerosis, systemic sclerosis, asthma, chronic obstructive pulmonary disease, inflammatory bowel disease (e.g., Crohn's and ulcerative colitis). The use of the protease binding protein allows a lower dose of the other therapeutic agents to be used in the methods and compositions, such that side effects of the other therapeutic agents are reduced or removed.
L'invention concerne des procédés et des compositions qui utilisent des protéines de liaison de protéase en combinaison avec d'autres agents thérapeutiques pour traiter des troubles inflammatoires tels que l'arthrite rhumatoïde, le psoriasis, la sclérose en plaques, la sclérose généralisée, l'asthme, une maladie pulmonaire obstructive chronique, une maladie intestinale inflammatoire (par exemple la colite de Crohn et la colite ulcéreuse). L'utilisation de la protéine de liaison de protéase permet d'utiliser une plus petite dose des autres agents thérapeutiques dans les procédés et compositions, de sorte que les effets secondaires des autres agents thérapeutiques sont réduits ou éliminés.
Dyax Corp.
Smart & Biggar
LandOfFree
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