Combination vaccine with whole cell pertussis

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/05 (2006.01) A61K 39/08 (2006.01) A61K 39/10 (2006.01) A61K 39/102 (2006.01) A61K 39/13 (2006.01) A61K 39/29 (2006.01)

Patent

CA 2741393

The present invention relates to a combination vaccine comprising a mixture of antigens for protection against dis-eases such as diphtheria, tetanus, whole cell pertussis and polio. The present invention also relates to inclusion of one or more antigens in the said combination vaccine, for protection against infections caused by Haemophilus influenzae, Hepatitis virus, and other pathogens, such that administration of the vaccine can simultaneously immunize a subject against more than one pathogen. The invention in particular relates to a fully liquid stable combination vaccine comprising the antigens as indicated above and the methods for manufacturing the same.

La présente invention concerne un vaccin combiné comprenant un mélange d'antigènes pour la protection contre des maladies telles que la diphtérie, le tétanos, la coqueluche (vaccin cellulaire entier) et la polio. La présente invention concerne aussi l'inclusion d'un ou de plusieurs antigènes dans ce vaccin combiné, pour la protection contre des infections par Haemophilus influenzae, le virus de l'hépatite, et d'autres pathogènes, de sorte que l'administration de ce vaccin puisse simultanément immuniser un sujet contre plus d'un pathogène. Cette invention en particulier concerne un vaccin combiné stable, complètement liquide, comprenant les antigènes tels que susmentionnés et les procédés de fabrication de ce vaccin.

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