Combinations comprising alpha-2-delta ligands and ep4...

Details Combinations comprising alpha-2-delta ligands and ep4... Combinations comprising alpha-2-delta ligands and ep4...

A - Human Necessities

61

K

A61K 31/196 (2006.01) A61K 45/06 (2006.01) A61P 25/02 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2563356

The instant invention relates to a combination of an EP4-receptor antagonist and an alpha-2-delta ligand, and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof and their use in the treatment of pain, particularly inflammatory, neuropathic, visceral and nociceptive pain.

La présente invention concerne une combinaison d'un antagoniste de récepteur EP4 et d'un ligand de alpha-2-delta, et des sels pharmaceutiquement acceptables et compositions pharmaceutiques de ces combinaisons, ainsi que leur utilisation dans le traitement de douleurs, notamment de douleurs inflammatoires, neurpathiques, viscérales et nociceptives.

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