Combinations comprising antimuscarinic agents and...

A - Human Necessities – 61 – K

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A61K 31/439 (2006.01) A61K 31/138 (2006.01) A61K 31/167 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01)

Patent

CA 2568568

A combination which comprises (a) a .beta.2 agonist and (b) an antagonist of M3 muscarinic receptors which is (3R)-1-phenethyl-3-(9H-xanthene-9- carbonyloxy)-1-azoniabicyclo[2.2.2]octane, in the form of a salt having an anion X, which is a pharmaceutically acceptable anion of a mono or polyvalent acid.

Combinaison contenant (a) un agoniste .beta.2 et (b) un antagoniste des récepteurs muscariniques M3 consistant en (3R)-1-phénéthyl-3-(9H-xanthène-9-carbonyloxy)-1-azoniabicyclo[2.2.2]octane, sous forme d'un sel possédant un anion X acceptable sur le plan pharmaceutique d'acide polyvalent ou de monoacide.

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